During the menopause, women often experience hormonal changes that can lead to weight gain, particularly an increase in abdominal fat. Ths shift not only affects how well look and feel but also increases the risk of various health issues. Hormone Replacement Therapy (HRT) has been studied for its potential in managing weight gain and reducing health risks.

HRT and Weight Management
Research suggests that HRT may help mitigate menopause-related weight gain. A study published in Maturitas found that combined HRT not only prevented weight gain but also promoted weight loss by significantly increasing lipid oxidation after three mopnths of treatment. Improvements were also observed in insulin respinse and plasma lipid profiles.
Supporting this, a study in Menopause reported that postmenopausal women undergoing HRT experienced a higher percentage of total body weight loss when treated with semaglutide, a medication used for weight management, compared to those not on HRT. This suggests a synergistic effect of HRT in enhancing weight loss efforts.
Importance of Maintaining Optimal Weight During Menopause
Achieving and maintaining an optimal weight during menopause is crucial for overall health. Excess bodyweight, especially around our abdomen, is associated with an increased risk of cardiovascular disease, type 2 diabetes and certain types of cancer. The Journal of Clinical Investigation highlighted that during the menopause transition, women experience significant increases in fat mass and declines in lean mass (muscle), which can adversely affect metabolic health.
Journal of Clinical Investigation
Moreover, the Journal of Mid-Life Health highlighted that menopause is linked to changes in body composition, notably the accumulation of visceral fat. This type of fat is especially concerning due to its association with metabolic syndrome and cardiovascular disease.
HRT can play a supporting role in managing weight during menopause by influencing body composition and improving the effectiveness of weight loss interventions. Maintaining an optimal weight is crucial to reduce the risk of various health complications associated with menopause-related weight gain. Women considering HRT for weight management should consult their doctor to discuss potential benefits and risks.